The Insilico PET®
Platform

A complete AI imaging suite — from deep-learning core engine to clinical integration — designed to bring functional imaging to every diagnostic setting worldwide.

How Insilico PET® Works

Insilico PET® is built on a conditional generative deep learning architecture, trained end-to-end on a large, multi-institutional dataset of paired CT and PET acquisitions. The model learns the complex, non-linear relationship between anatomical CT features and the underlying functional metabolic state of tissue.

At inference time, a DICOM CT series is passed through the model, which outputs a synthetic PET volume at full spatial resolution. The output is quantified in standardised uptake value (SUV) units, directly comparable to a true PET acquisition, and delivered as a standard DICOM series.

Our model architecture incorporates uncertainty quantification, providing clinicians with confidence maps alongside each functional output — enabling informed, safety-conscious clinical decision-making.

CT DICOM 512×512×N Insilico PET® AI Synthetic PET SUV DICOM out Input: Standard CT Deep learning model Output: Functional map

Clinical Applications

Insilico PET® is available across six complementary clinical and research use cases, each built on the same validated core engine.

Oncology Imaging

Generate functional metabolic maps from CT to identify primary tumours, metabolically active lymph nodes, and distant metastases. Supports initial staging, mid-treatment response assessment, and end-of-treatment evaluation across lung, colorectal, head and neck, and other solid tumours.

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Neurology Imaging

Map cerebral glucose metabolism to support early diagnosis of Alzheimer's disease, Parkinson's disease, Lewy body dementia, and other neurodegenerative conditions. Our model captures hypometabolic patterns characteristic of neurodegeneration, enabling earlier intervention.

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Cardiology Imaging

Assess myocardial viability, perfusion defects, and inflammatory cardiac disease from standard cardiac CT. Provides functional data critical for decisions around coronary revascularisation, device implantation, and heart failure management.

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Pharmaceutical R&D

Incorporate functional imaging endpoints into clinical trials at a fraction of the cost and logistical complexity of conventional PET. Insilico PET® enables metabolic response biomarkers in Phase II and III trials without requiring PET-capable sites or radiotracer supply chains.

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Clinical Integration

A DICOM-native, HL7-compatible API that slots into existing PACS, RIS, and EHR environments. Insilico PET® outputs appear directly in the radiologist's reading workstation alongside standard CT series — zero workflow disruption.

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Academic Research

Collaborate with RADiCAIT on funded research programmes. We provide access to our models, datasets, and technical team for university and NHS research partners investigating AI in medical imaging, with co-publication opportunities.

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Built on Rigorous Clinical Evidence

Insilico PET® has been developed and validated against ground-truth PET imaging across thousands of paired cases. Our validation programme spans multiple institutions, patient demographics, and clinical indications to ensure robust real-world performance.

We measure performance using standardised metrics including SUV concordance, Dice coefficient for lesion segmentation, and overall diagnostic accuracy benchmarked against radiologist reads of true PET images.

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94%
Diagnostic concordance
3
Validated clinical areas
4+
Years of R&D
100M+
Addressable patients p.a.

From Deployment to Daily Clinical Use

RADiCAIT handles the full implementation journey — from initial integration to ongoing model updates and clinical support.

1

Discovery & Scoping

We work with your IT and radiology teams to map existing infrastructure and define integration requirements, timelines, and success metrics.

2

API Integration

Our DICOM-native API is configured to your PACS environment. Typical integration takes 2–4 weeks. No new hardware required.

3

Go-Live & Support

Dedicated onboarding, radiologist training, and ongoing technical support. Continuous model improvements are deployed automatically.

Ready to Bring Functional Imaging to Your Institution?

Request a personalised demo and see Insilico PET® applied to your imaging use case.